Find Relief
with Spravato
Breakthrough option for Treatment-Resistant Depression in Minneapolis, Greater Minnesota, and Wisconsin.
Spravato (esketamine)
Spravato (Esketamine) nasal spray is a significant advancement in the fight against treatment-resistant depression and major depressive disorder (MDD), offering a new avenue for those who have not found relief through traditional treatments. This therapy is a potential option for adults who have struggled with persistent depressive symptoms despite conventional treatment efforts.
what is spravato?
Spravato is an FDA-approved nasal spray treatment for adults with treatment-resistant depression who are taking an antidepressant and still having symptoms of depression and/or suicidal thinking. Spravato contains a form of Ketamine called Esketamine that studies have shown to have strong, rapid antidepressant effects. Taking an antidepressant is still a requirement for Spravato therapy.
how does Spravato work?
Spravato works by delivering Esketamine directly into the nasal passage, where it is quickly absorbed into the bloodstream. Spravato targets glutamate receptors in the parts of the brain involved in mood regulation and has been shown to relieve symptoms of depression relatively quickly compared to traditional antidepressants.
Approved by the FDA in March 2019, Spravato offers a new hope for individuals who haven’t found success with other depression treatments.
What are the benefits of Spravato?
- Patients often experience an improvement in depressive symptoms within hours or days, much faster than most conventional antidepressants.
- Being a nasal spray, Spravato is non-invasive and can be administered easily in a clinical setting under the supervision of healthcare professionals.
Who can benefit from Spravato?
Spravato is specifically designed for adults who suffer from treatment-resistant depression or major depressive disorder and have not responded adequately to traditional antidepressant therapies. It is an option for those seeking alternatives after other treatments have failed.
Please note, Spravato is not suitable for everyone. It is our goal to provide individualized patient-centered care to each person we serve. We will carefully assess each individual’s physical, mental, and emotional well-being before recommending Spravato.
Your Path to Healing Starts Here
Consultation with
our expert team
Personalized treatment
plan development
Ongoing support
and monitoring
Your Partner in Recovery
Committed to Your Mental Wellness
At The Remedy, expertise and empathy go hand in hand, providing a supportive environment that mirrors the esteemed care of top academic medical centers. Here, every individual is a partner in their path to wellness, and every treatment is a step toward a brighter, more promising tomorrow. Every one of our team members in Minneapolis, Greater Minnesota, and Wisconsin is dedicated to ensuring your Spravato treatment is as effective as possible while your experience during every visit is comfortable and caring.
What Our PAtients Say
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– Margret F.
Spravato FAQ
How effective is Spravato?
In a clinical study lasting four weeks, Spravato improved symptoms of depression in people taking the drug — most notably in the first 24 hours after taking it. In an additional year-long study of those who saw the most dramatic improvements in their symptoms, Spravato continued to improve depression symptoms. During this study, people took an oral antidepressant with either Spravato or a placebo nasal spray. Those who took Spravato were 51% to 70% less likely to relapse back to severe depression than those taking the placebo.
Is Spravato as effective as IV ketamine treatments?
There are no current head-to-head studies comparing the effectiveness of Spravato to IV ketamine infusions. Based on the experience of practitioners using compounded intranasal ketamine vs. IV ketamine infusions, ketamine infusions appear to have a more robust effect in treating depression and can also be individually adjusted to provide the effectiveness you need.
Can I take Spravato at home?
Although it is given as an intranasal spray, the FDA has highly regulated Spravato and requires that the medication either be sent by the pharmacy directly to the practitioner’s office or purchased from the practitioner’s office. The FDA has also required that Spravato be administered in the practitioner’s office with a two-hour post-application monitoring period in the office.
Does insurance cover Spravato?
You can check with your insurance provider as to whether Spravato is a covered service for you, both the medication and application in the office /post-application monitoring period. As it is a brand name drug, without insurance, Spravato is quite expensive without insurance.
How many treatments of Spravato will I need?
The current recommended treatment protocol is for twice a week of treatment for the first four weeks, then weekly treatments for weeks five through nine. Thereafter, treatment frequency is once every one to two weeks. Currently, there are no studies of Spravato for longer than a year.
