In-Clinic Spravato Treatment in Minnesota, Wisconsin, and South Dakota
Trying different medications or treatments without finding enough relief can be frustrating. Spravato is a prescription esketamine nasal spray that may be considered for adults with treatment-resistant depression. Treatment takes place in a monitored clinic setting. Our team helps patients understand whether Spravato may be appropriate, what insurance may require, and what to expect throughout treatment.
Spravato is an FDA-approved prescription nasal spray containing esketamine. It may be considered for adults with treatment-resistant depression who have not improved enough after trying other antidepressant medications.
Spravato works differently from traditional antidepressants by affecting a chemical messenger in the brain called glutamate, which may help reduce depression symptoms for some patients.
Spravato may be considered for adults who:
Spravato is not appropriate for everyone. Before recommending treatment, our team will review your symptoms, health history, medications, previous treatments, and individual needs.
Spravato® and IV ketamine are related treatments, but they are not the same. While both are administered in a monitored clinical setting, they use different forms of medication and are delivered in different ways. Neither treatment is the right choice for every patient. Your provider can review your symptoms, medical history, previous treatments, insurance coverage, and personal preferences to help determine which option may be the best fit for your needs.
Spravato contains esketamine and is used as a nasal spray. You administer the spray yourself under the supervision of our care team and remain at the clinic for monitoring afterward. Spravato is FDA-approved for certain adults with depression and must be provided through a SPRAVATO® REMS-certified treatment setting.
IV ketamine is delivered directly into a vein through an infusion. Although ketamine is an FDA-approved medication, its use for depression is considered off-label. Your provider monitors you throughout the infusion and recovery period.
Your provider reviews your symptoms, health history, medications, previous treatments, and goals.
Our team will review your insurance information and any prior-authorization requirements.
Explain preparation, transportation, and appointment-day instructions and ensure you are ready for treatment.
You will use the Spravato nasal spray under staff supervision. After treatment, you will remain at the clinic for at least two hours for monitoring.
Our team checks your comfort and progress throughout treatment. Your provider will discuss follow-up care and any recommended next steps.
Our team can help match you with the right provider and answer any questions you may have along the way.
The Remedy provides support throughout the entire Spravato process, from your initial evaluation and insurance review to treatment clearance and ongoing appointments. As a SPRAVATO® REMS-certified treatment setting, we follow the required safety and monitoring guidelines for providing Spravato in the clinic. Our team helps patients understand what to expect, answers questions throughout treatment, and coordinates care based on each person’s individual needs.
The Remedy also offers:
Your provider can help determine whether Spavato may be a beneficial part of your overall mental health care plan. Treatment is available at select clinics across Minnesota, Wisconsin, and South Dakota.
The Remedy Mental Health provides care across Minnesota, Wisconsin and South Dakota. Our clinics provide Spravato treatment in the Twin Cities, Minneapolis, St. Paul, Burnsville, Golden Valley, Maple Grove, Vadnais Heights, Eau Claire, Hudson, Rapid City and surrounding communities.
Our Spravato providers offer personalized evaluations, treatment planning, and ongoing support throughout your course of care.
Insurance may cover Spravato, but coverage and out-of-pocket costs vary by plan. Prior authorization is often required, and your insurance company may request information about your diagnosis and previous depression treatments.
Our team will review your benefits, explain any insurance requirements, and submit the necessary information before treatment begins. Final approval and costs, including any deductible, copay, or coinsurance, are determined by your insurance company.
No, you do not need a referral to contact The Remedy about Spravato treatment. Our team can help you get started, schedule an evaluation, and determine whether Spravato may be appropriate for you. Some insurance plans may have their own requirements before treatment is approved.
Each person’s experience is different. During or shortly after treatment, you may feel sleepy, dizzy, lightheaded, relaxed, or slightly disconnected from yourself or your surroundings. Some people experience changes in how things look, sound, or feel, while others notice very little. Nausea, anxiety, or a temporary increase in blood pressure may also occur.
Our team will monitor you throughout your appointment and check in on how you are feeling. These effects commonly begin soon after treatment and often lessen before you leave the clinic.
No. You will need to arrange for someone to drive you home after each Spravato appointment. You should not drive, operate machinery, or do anything that requires your full attention until the next day after a restful night of sleep—even if you feel well enough to do so.
Spravato treatment typically begins with two appointments per week for the first four weeks. After that, treatment may continue once per week or every other week, depending on your response and individual treatment plan.
Your provider will review your progress and determine how often treatment should continue. Insurance requirements may also affect the approved schedule.
